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Tissue engineering: current state and perspectives

Summary

This article discusses the current state and perspectives of tissue engineering, an interdisciplinary field which seeks to create new tissues and organs. It covers the advances made in various aspects of tissue engineering, including materials design, reactor design, and cell source, as well as how progenitor and stem cells play a critical role in understanding and developing new engineered tissues. It also discusses complementary technical tools to design functional bioartificial tissues, advances in osteochondral tissue engineering, the Charleston Bioengineered Kidney Project, stem cells and tissue engineering, and graphene-related nanomaterials for biomedical applications.

Q&As

What is tissue engineering and what is its goal?
Tissue engineering is an interdisciplinary field that involves cell biology, materials science, reactor engineering, and clinical research with the goal of creating new tissues and organs.

What advances have been made in tissue engineering?
Significant advances in tissue engineering have been made through improving singular aspects within the overall approach, e.g., materials design, reactor design, or cell source. Increasingly, however, advances are being made by combining several areas to create environments which promote the development of new tissues whose properties more closely match their native counterparts.

What role do progenitors and stem cells play in tissue engineering?
Progenitors and stem cells play a critical role in understanding and developing new engineered tissues as part of this approach.

What are some examples of tissue engineering applications?
Examples of tissue engineering applications include osteochondral tissue engineering, the Charleston Bioengineered Kidney Project, and stem cells and tissue engineering.

What are the current trends in tissue engineering?
Current trends in tissue engineering include the use of graphene-related nanomaterials for biomedical applications, the controlled release of H2S from biomimetic silk fibroin-PLGA multilayer electrospun scaffolds, advancement in nanostructure-based tissue-engineered biomaterials for retinal degenerative diseases, and injectable biomaterials for dental tissue regeneration.

AI Comments

👍 This article provides a comprehensive overview of the current state and perspectives of tissue engineering, including progenitors and stem cells, materials engineering, and reactor design.

👎 This article lacks a discussion of the potential ethical implications of tissue engineering and the potential risks associated with the use of stem cells.

AI Discussion

Me: It's about tissue engineering and the current state of the field. It talks about the advances made in the field, the use of progenitors and stem cells to understand and develop new tissues, and the potential for creating bioartificial organs.

Friend: That's really interesting. What are the implications of this article?

Me: The implications of this article are that tissue engineering has a lot of potential for medical applications. For example, the article mentions that researchers are trying to create bioartificial organs, which could potentially replace or augment existing organs in the body. Additionally, the use of stem cells and progenitors to create new tissues could be used to treat a wide range of diseases or injuries. These advances could have a major impact on healthcare, as they could provide more effective treatments and therapies for many medical conditions.

Action items

Technical terms

Tissue engineering
A field of science that combines cell biology, materials science, reactor engineering, and clinical research with the goal of creating new tissues and organs.
Progenitors and stem cells
Cells that have the potential to develop into different types of cells.
Bioartificial organs
Artificial organs created using biological materials.
Biomedical engineering
The application of engineering principles and techniques to the medical field.
Biocompatible materials
Materials that are compatible with living tissue and do not cause an adverse reaction.
Reactor engineering
The design and operation of reactors for chemical and biological processes.
Forecasting
The process of predicting future events or trends.

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