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An Urgent Update to the Global Demyelination Epidemic Hypothesis โ€“ Sudden Deaths/Long COVID explained?

Summary

This article proposes that COVID vaccination can induce autoimmune attacks against myelin, which can lead to sudden cardiac deaths and long-term COVID symptoms such as brainstem dysfunction. The article presents two case studies of patients with multiple sclerosis whose sudden deaths were caused by active demyelination of their medulla oblongata. The author urges for more research into this hypothesis, and suggests that histology of the brainstem be conducted on all sudden cardiac deaths of those under 60.

Q&As

What is the hypothesis of the global demyelination epidemic?
The hypothesis of the global demyelination epidemic is that Long COVID and many of the Sudden Deaths occurring can be explained by demyelination.

What research has been conducted regarding the link between COVID-19 vaccination and multiple sclerosis?
Research has been conducted that shows that COVID-19 vaccination can induce multiple sclerosis via cross-reactive CD4+ T cells recognizing SARS-CoV-2 spike protein and myelin peptides.

What is the proposed connection between long-COVID and brainstem dysfunction?
The proposed connection between long-COVID and brainstem dysfunction is that SARS-CoV-2 may exhibit tropism in the brainstem due to its relatively high expression of ACE2 receptor compared with other brain regions, and that persistent brainstem dysfunction may be involved in long-COVID.

What is the case report of sudden cardiac death in multiple sclerosis?
The case report of sudden cardiac death in multiple sclerosis is that a patient with active relapsing-remitting MS died unexpectedly due to the sudden onset of cardiac arrythmias, and post-mortem examination showed the presence of active demyelinating lesions in the medulla oblongata.

What is the recommended course of action to determine if this hypothesis is accurate?
The recommended course of action to determine if this hypothesis is accurate is to conduct histology of the Brainstem on all Sudden Cardiac Deaths in those under 60.

AI Comments

๐Ÿ‘ This article provides a comprehensive look into the Global Demyelination Epidemic Hypothesis and the potential link between the COVID Vaccine and MS/AI. The research presented is thorough and provides evidence for the hypothesis.

๐Ÿ‘Ž The article does not provide a solution to the Global Demyelination Epidemic Hypothesis, leaving readers with more questions than answers. Furthermore, the need for histology of the Brainstem on all Sudden Cardiac Deaths in those under 60 is not fully addressed.

AI Discussion

Me: It's about a global demyelination epidemic hypothesis that could explain sudden deaths and long-term COVID effects. It talks about how the WHO website has found that the COVID vaccine can induce an autoimmune attack against myelin, which is the substance that insulates nerve cells, and how this could be the cause of these sudden deaths. It also talks about how there could be persistent brainstem dysfunction in long-COVID cases, which could also be linked to demyelination. Finally, it presents a case report of a patient with active relapsing-remitting MS who died suddenly due to cardiac arrhythmia, which was caused by active demyelination of the medulla oblongata.

Friend: Wow, that's really concerning. It seems like this could have really serious implications if this turns out to be true.

Me: Yeah, it's definitely something that needs to be investigated further. We need to figure out if this is really the cause and if so, what can be done to prevent or mitigate it.

Action items

Technical terms

Demyelination
The destruction or damage of the myelin sheath, a protective layer that surrounds nerve cells.
Multiple Sclerosis (MS)
A chronic, inflammatory, autoimmune disorder of the central nervous system that affects the brain, spinal cord, and optic nerves.
ACE2 Receptor
A protein found on the surface of cells that binds to the spike protein of the SARS-CoV-2 virus, allowing it to enter the cell.
Cardiac Arrythmias
Abnormal heart rhythms that can cause the heart to beat too fast, too slow, or irregularly.
Medulla Oblongata
A part of the brainstem that controls vital functions such as breathing, heart rate, and blood pressure.

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